Peculiarities of Allergy to Tree Pollen and Approaches to Diagnosis and Allergen Immunotherapy in Patients – Residents of Lviv Region

The study involved 286 patients (17-58 years, 55.9% females and 44.1% males). SPT was performed with extracts “Mixture of trees” (Diater Laboratorios, Spain). The study of allergen components was made by ImmunoCAP. We evaluated the efficiency of SLIT by visual analogue scale. 98.3% patients had positive SPT to extract “Mixture of trees”. N=281:191 (68.1%) individuals were positive to birch extract, 8 (2.8%) – to ash tree, 82 (29.1%) – to birch+ash tree. Ash sensitization according to SPT – 31.9%. ImmunoCAP: among patients with positive SPT to birch, true sensitization – in 147 (77%) individuals, among patients with polysensitization – 63 (76.9%). The number of patients with minor components in both groups was similar – 21.1%. The results revealed a significant decrease in the severity of symptoms in experimental group after one (83.1%) and two years (94.1%) of treatment. SLIT by combined vaccine “Spring Tree” demonstrates high efficiency for patients with sensitization to Betulacea and Oleaceae.